Identifying genetic relatives without compromising privacy

Identifying genetic relatives without compromising privacy.

The development of high-throughput genomic technologies has impacted many areas of genetic research. While many applications of these technologies focus on the discovery of genes involved in disease from population samples, applications of genomic technologies to an individual's genome or personal genomics have recently gained much interest. One such application is the identification of relativ...

Protecting Privacy of Shared Epidemiologic Data without Compromising Analysis Potential

OBJECTIVE Ensuring privacy of research subjects when epidemiologic data are shared with outside collaborators involves masking (modifying) the data, but overmasking can compromise utility (analysis potential). Methods of statistical disclosure control for protecting privacy may be impractical for individual researchers involved in small-scale collaborations. METHODS We investigated a simple a...

Privacy preserving protocol for detecting genetic relatives using rare variants

MOTIVATION High-throughput sequencing technologies have impacted many areas of genetic research. One such area is the identification of relatives from genetic data. The standard approach for the identification of genetic relatives collects the genomic data of all individuals and stores it in a database. Then, each pair of individuals is compared to detect the set of genetic relatives, and the m...

Efficient Logging without Compromising Testability

Cryptography for Secure and Private Databases: Enabling Practical Data Access without Compromising Privacy

IN 2006 America Online’s research division leaked the web search histories of more than 600,000 of their customers. While this data had been stripped of customer names and identifying information, it nevertheless revealed deeply private information about these individuals’ identities and interests. Access to information is becoming fundamental to our society, whether it is a web search or a loo...